More information

What is mesothelioma?

Malignant mesothelioma is a cancer of the lining of the chest commonly caused by exposure to asbestos. There is no cure for mesothelioma. Chemotherapy can help for some patients, but not all.

I am a patient with mesothelioma - can I take part?

Unfortunately, we can not just take all patients into the study. Your local specialist centre will have to be taking part in the study. Also, studies like these usually have quite strict criteria as to who can take part - this is to make sure the right answers are found to make the study safe and worthwhile. The link below shows which hospitals are taking part in this study.  We suggest you speak to your local specialist or the study team (link to email) to find out more.

Which hospitals are taking part in this study?

Queen Alexandra Hospital, Portsmouth Norfolk and Norwich University Hospital University Hospital North Durham & Darlington Hospital North Manchester General Hospital South Tyneside District Hospital New Cross Hospital, Wolverhampton Broomfield Hospital, Essex Southmead Hospital, Bristol Royal Gwent Hospital, Wales Musgrove Park Hospital, Taunton Great Western Hospital, Swindon Wythenshawe Hospital, South Manchester Basildon Hospital, Essex Sir Charles Gairdner Hospital, Perth, Australia (in set-up) City Hospital & Sandwell Hospital, Birmingham (in set-up) Royal Hampshire County Hospital & Basingstoke Hospital (in set-up) North Tyneside General Hospital Southampton General Hospital Ipswich Hospital Wansbeck General Hospital Royal Hampshire County Hospital

What will happen to the results of the study?

Studies of this sort normally publish results in a medical journal and can be presented and discussed in Doctor's conferences. Participants will not be identified in any way in the report.

What is palliative care?

Palliative Care provides physical (symptoms), emotional (stress, worry) and spiritual (not religious) support for patients and families that can be at any time during an illness. We would like to know if involving these specialists much earlier than usual makes a difference for patients and carers.

About asbestos

Asbestos is a mineral mined from the ground. Many industrial countries used and imported asbestos throughout most of the 20th Century; in the United Kingdom importation of asbestos only ceased in 1999. "Asbestos" comes from a Greek adjective meaning 'inextinguishable'. Historic records suggest asbestos has been used by man for over 4,000 years; it became increasingly popular throughout the 20th Century amongst manufactures and builders due to its resistance to heat, electricity and chemical damage, its sound absorption and tensile strength. Many of these properties made asbestos an ideal material for use in ship building, and vast tonnes of asbestos were used for this purpose during the second world war and beyond by the UK and other industrialised nations. The use of asbestos in homes, schools, hospitals and indeed almost any building erected in the UK after 1960 became almost ubiquitous. Whilst use of asbestos in industry and as a building material has stopped, there may still be exposure to asbestos through home renovation and building works in old buildings.

Who has reviewed this study? Is it safe?

All research in the NHS is looked at by an independent group of people called a Research Ethics Committee. They are there to protect you. This study has been given a favourable opinion by the North London Hampstead Research Ethics Committee (reference 12/LO/0078). This means they have read about the study, interviewed the lead Doctor and have no concerns with this project.

Why randomly choose patients for this extra treatment?

Sometimes we don't know which treatments are best. To find out, we need to compare different treatments. We put people into different groups and give each group different treatment. The results are then compared to see which one is better. To try to make sure the groups are the same at the start, each patient is put into a group by chance (randomly).

Useful links for the UK

British Lung Foundation  The National Council for Palliative Care  Our study page on the Cancer Research UK website Mesothelioma UK 

What is


Malignant mesothelioma is a rare cancer of the lining of the chest commonly caused by exposure to asbestos. This exposure may have occurred up to forty years earlier. Mesothelioma usually causes symptoms like breathlessness, loss of weight and chest pain, but it can affect people in different ways. There is no cure for mesothelioma. This study seeks to learn how best we can support patients with mesothelioma and their families.
A study to learn more about treating malignant mesothelioma - can we improve quality of life?


(All the downloads below are PDF files) Frequently Asked Questions Patient information sheet Carer information sheet Patient consent sheet Carer consent sheet Carer GP Letter Study protocol Invitation to participate Poster

Interested in

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For more information including eligibility criteria and resource implications for your centre – select this link